• Disease-specific outcomes of Radical Prostatectomies in Northern Norway; A case for the impact of perineural infiltration and postoperative PSA-doubling time 

      Andersen, Sigve; Richardsen, Elin; Nordby, Yngve; Ness, Nora; Størkersen, Øystein; Al-Shibli, Khalid; Dønnem, Tom; Bertilsson, Helena; Busund, Lill-Tove; Angelsen, Anders; Bremnes, Roy M. (Tidsskriftartikkel; Journal article; Peer reviewed, 2014)
      Background Prostate cancer is the most common male malignancy and a mayor cause of mortality in the western world. The impact of clinicopathological variables on disease related outcomes have mainly been reported from a few large US series, most of them not reporting on perineural infiltration. We therefore wanted to investigate relevant cancer outcomes in patients undergoing radical prostatectomy ...
    • Presence of TMPRSS2-ERG is associated with alterations of the metabolic profile in human prostate cancer 

      Hansen, Ailin Falkmo; Sandsmark, Elise; Rye, Morten Beck; Wright, Alan J; Bertilsson, Helena; Richardsen, Elin; Viset, Trond; Bofin, Anna M.; Angelsen, Anders; Selnæs, Kirsten Margrete; Bathen, Tone Frost; Tessem, May-Britt (Tidsskriftartikkel; Peer reviewed; Journal article, 2016-06-03)
      TMPRSS2-ERG has been proposed to be a prognostic marker for prostate cancer. The aim of this study was to identify changes in metabolism, genes and biochemical recurrence related to TMPRSS2-ERG by using an integrated approach, combining metabolomics, transcriptomics, histopathology and clinical data in a cohort of 129 human prostate samples (41 patients). Metabolic analyses revealed lower con ...